I too feel sad at times when I want company but have no friends or family around. Twitter is no different from the physical real. Sometimes those you know are busy doing something else that, in that moment, is more important to them than you are. The difference is that the nature of the technology is such that it can enhance feelings of loneliness as you can ‘see’ what those you know are doing. This would never be the case in the physical real. You do not get to see what those you know are doing when you are not with them. My advice as the headless shrink is to look at Twitter as if it were the physical real – get into the habit of not checking what others are doing unless they are sending resources for everyone. It is never good for loneliness to read other people’s private chats even the technology allow you to.